Sundharraman Subramanian

The paper investigates two LarA-like enzymes lacking a catalytic histidine residue, solving their structures and revealing a novel octameric assembly and active site residues involved in carbohydrate metabolism.

This study investigates how bacteriophage MS2 coat proteins selectively package viral RNA over host RNA, finding that selectivity arises from collective interactions rather than a single stem-loop.

The paper reports that E. coli heteromeric acetyl-CoA carboxylase forms polymorphic helical tubular filaments, revealing protein-protein interactions that support catalysis and mask transcriptional regulation.