Dexin Sui

The paper investigates two LarA-like enzymes lacking a catalytic histidine residue, solving their structures and revealing a novel octameric assembly and active site residues involved in carbohydrate metabolism.

This study investigates the mechanism of metal substrate translocation in the ZIP transporter BbZIP using structural, biochemical, and computational methods, revealing unique conformational changes and transport dynamics.

This study rationally engineers ZIP8 to alter its substrate specificity, identifying a conditional selectivity filter that determines substrate preference based on transporter conformation.

The paper reports a high-resolution crystal structure of a mercury-crosslinked ZIP transporter, revealing dynamic motions and a metal relay mechanism for zinc transport.