Paul E. M. Phillips

This study investigates how nucleus accumbens dopamine responds to reward-related stimuli during trace conditioning, finding bidirectional dopamine changes correlate with response latency.

This study investigates the role of CRF-R1 in the Nucleus Accumbens in cocaine consumption and finds that inhibiting or deleting CRF-R1 does not reduce cocaine escalation.

This study shows that KOR on VTA neurons, not NAcC neurons, prevents cocaine escalation by blocking the transition to SUD-like behavior.

The study finds that senescent male rats show reduced phasic dopamine signaling but still maintain dopamine-dependent Pavlovian conditioning.

This study shows that L-DOPA reduces alcohol and opioid self-administration in rats, suggesting a role for dopamine signaling in drug consumption across multiple substance classes.

The paper shows that cocaine seeking and taking are oppositely regulated by dopamine in rats, with cue-evoked dopamine changes linked to relapse and escalated consumption.

This study shows that repetitive blast exposure in mice leads to chronic aversive responses to environmental cues, unlike single exposures, highlighting the complex effects of repeated trauma.