Author

Samantha L. Tinsley

Purdue University West LafayetteORCID 0000-0002-8761-5504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alisha DhimaniD· 1 shared Brittany L. Allen-PeterseniD· 1 shared Colin J. DanieliD· 1 shared Ella Rose D. ChianisiD· 1 shared Emily C. DykhuizeniD· 1 shared Gaganpreet K. Mall· 1 shared Garima BaraliD· 1 shared Goutham NarlaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alisha DhimanORCID

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1 paper

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedOct 23, 2024

KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development

Samantha L. Tinsley, Ella Rose D. Chianis, Rebecca A. Shelley…·Brittany L. Allen-Petersen

This study shows that KRASG12D upregulates CIP2A, which inhibits PP2A-B56α, leading to c-MYC stabilization and promoting pancreatic cancer initiation.

9 citations

mouseexperimental assay

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