Goutham Narla

This study identifies PP2A inactivation as a key driver of myocardial injury in TTS, showing that restoring PP2A or inhibiting JNK reduces ferroptosis and mitochondrial dysfunction.

This study shows that PP2A activation inhibits macropinocytosis and induces cell death in pancreatic ductal adenocarcinoma, suggesting PP2A activators could be used with metabolic inhibitors as a new therapeutic strategy.

This study shows that SRG rats support better human tumor growth and microenvironment interactions compared to NSG mice, despite similar immunodeficiency levels.

This study identifies the cooperative role of c-MYC and KLF6-SV1 in promoting prostate cancer progression and metastasis through proteomic and genetic analyses in mouse models.