TRIM52 downregulates IFN-β production by targeting TBK1 for proteasome degradation.
This study identifies TRIM52 as a negative regulator of IFN-β production by promoting TBK1 ubiquitination and proteasomal degradation.
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University of CalgaryORCID 0000-0002-8797-1322Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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This study identifies TRIM52 as a negative regulator of IFN-β production by promoting TBK1 ubiquitination and proteasomal degradation.
Yu Ye, Zhijun Yang, Mengzhou Xue, Chunfu Zheng
This study identifies ICP22 interaction with ASF1 proteins and shows their role in HSV-1 replication and transcription regulation.
Jie Wang, Yujing Deng, Dongyue Zhu…·Xiaofeng Zheng
This study identifies RAP80 as a target of HSV-1 ubiquitination enzymes ICP0 and UL36USP, showing how HSV-1 modulates host proteins at different infection stages to promote its survival.
M. Nazmul Hoque, Md. Arif Khan, Md. Arju Hossain…·Tofazzal Islam
The paper identifies differentially expressed genes (DEGs) in COVID-19 patients and recovered individuals using machine learning, revealing potential biomarkers and therapeutic compounds.