Lin Sun

This study investigates the role of RNA m6A modification in aneuploid Drosophila, showing its impact on gene regulation and developmental abnormalities through interactions with the MSL complex and dosage compensation mechanisms.

The paper analyzes transcriptome data from human aneuploidies to show inverse or proportional trans-modulation of genes on unvaried chromosomes and compensation on varied chromosomes, with differences observed between autosomal and sex chromosome aneuploidies.

The paper identifies AC9 as a key regulator of ER calcium homeostasis during neuronal differentiation using CRISPR screening and functional analysis.