Sebastian Eves‐van den Akker

The paper investigates whether diversity at the HYP1 locus in potato cyst nematodes arises from developmental editing or sequencing errors, concluding it is due to evolutionary forces.

This study investigates how hatching time affects the parasitism of beet cyst nematodes, finding that late hatchers are more infective due to differences in energy use and gene expression.

The paper uses AlphaFold3 to predict a cross-kingdom interactome between Medicago truncatula and Sinorhizobium meliloti, identifying DNF2 as a key hub for host-symbiont communication.

This study uses 3D printing and deep learning to analyze parasite dynamics across hundreds of plant genotypes, identifying host genetic control of parasite traits and new QTLs.

This paper investigates how Meloidogyne incognita infects diverse plant species by analyzing transcriptomic responses across nine plant interactions, finding distinct transcriptional programs and effector deployment patterns that influence host specificity.

This study identifies two transcription factors in Bursaphelenchus xylophilus that non-redundantly regulate gene expression across its life cycle, with distinct roles in parasitism and reproduction.

This study identifies DGR-1 as a transcription factor that switches from lytic to biotrophic effector production in plant-parasitic nematodes, working antagonistically with SUGR-1 to regulate effector expression during infection.

This study identifies Hs2B11 as a nematode effector that interacts with AtPR-6 to suppress plant immunity and enhance parasitism.

The paper identifies trehalase-derived peptides as MAMPs that trigger LecRK-V-mediated immune responses in Arabidopsis, enabling broad-spectrum pathogen detection.

This paper develops an optimized dCas9-based CAPTURE method for studying DNA-protein interactions in the nematode Meloidogyne incognita, identifying chromatin-associated proteins involved in effector gene regulation.

This paper identifies SUGR1 as a master regulator in nematodes that orchestrates effector production, essential for host entry and parasitism, and shows blocking SUGR1 prevents parasitism.

This study identifies and characterizes the effectorome of the plant-parasitic nematode Heterodera schachtii, revealing 659 effector gene loci and providing insights into their origin, deployment, and evolution.

The paper discovers unprecedented allelic variation in HYP effectors of plant-parasitic nematodes, revealing a novel mechanism of programmed genetic variation called HVD-editing.

The paper identifies susceptibility genes involved in trans-kingdom vitamin B synthesis between a plant-parasitic nematode and its host, revealing a horizontal gene transfer critical for parasitism.

The paper analyzes the spatio-temporal gene expression of Meloidogyne incognita across its life stages and identifies a conserved promoter motif associated with effector genes.

This paper develops methods for delivering macromolecules and expressing exogenous mRNA in plant-parasitic nematodes, advancing functional genetic tools for these pests.

This study examines transcriptional changes in Myzus cerasi aphids across different host environments, finding extensive plasticity with redox-related genes and differential exon usage.

The paper assembles and annotates the genome of the soybean cyst nematode, revealing duplications and horizontal gene transfer events in effector genes involved in parasitism.

The paper analyzes aphid genomes to understand gene evolution and horizontal gene transfer, finding shared transcriptional control of effector genes involved in parasitism.