Jatin Roper

The paper identifies a mechanism by which commensal bacteria inhibit viral infections through a tryptophan metabolite that activates the aryl hydrocarbon receptor.

This study shows aging restricts colorectal tumor growth by epigenetically silencing developmental gene programs, with implications for early-onset colorectal cancer.

This study develops a co-culture system to study C. difficile interaction with human intestinal epithelium and finds CCL20 expression is upregulated in response to the bacterium.

This study shows Lgr5+ stem cells maintain intestinal epithelial homeostasis and drive regeneration after injury through WNT signaling.

This study identifies obesity-driven inflammatory and metabolic transcriptomic signatures in mouse and human colon tumors through integrated transcriptomic analyses.

This study investigates how nutrient supply affects ASNS and GPER1 expression in KRAS mutant and wild-type colorectal cancer cells and their association with patient survival.

This study uses deep learning to classify ex vivo human colon tissues with spectroscopic OCT, achieving 88.9% accuracy in distinguishing tissue types.