Author

Flavio Vasella

University of ZurichORCID 0000-0002-8953-0862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Guido ReifenbergeriD· 1 shared Michael WelleriD· 1 shared Remi WeberiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Guido ReifenbergerORCID

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1 paper

Recent·Most cited

Cancer BiologyFrontiers in OncologyPeer-reviewedJan 31, 2024

Epigenetic modification and characterization of the MGMT promoter region using CRISPRoff in glioblastoma cells

Remi Weber, Michael Weller, Guido Reifenberger, Flavio Vasella

This study uses CRISPRoff to introduce site-specific CpG methylation in the MGMT promoter of glioblastoma cells, showing reduced MGMT expression and increased temozolomide sensitivity.

6 citations

humanDNA methylation

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