Author

Stephen M. Matthews

Cleveland ClinicORCID 0000-0002-8968-225XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christine M. O’ConnoriD· 2 shared Amanda B. WassiD· 1 shared Brittany W. GeileriD· 1 shared Gary C. ChaniD· 1 shared Ian J. GrovesiD· 1 shared Jamil MahmudiD· 1 shared Julia E. MyersiD· 1 shared Juthi Biswas· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Christine M. O’ConnorORCID

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 26, 2024

Host-encoded CTCF regulates human cytomegalovirus latency via chromatin looping

Ian J. Groves, Stephen M. Matthews, Christine M. O’Connor

This study shows CTCF binding to the HCMV MIE locus maintains latency by enabling chromatin looping that represses transcription, which is lost during reactivation.

17 citationstop 4%

humanChIP-seq

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MicrobiologybioRxivPreprintSep 5, 2023

Virion-associated US28 rapidly modulates Akt activity to suppress HCMV lytic replication in monocytes

Jamil Mahmud, Brittany W. Geiler, Juthi Biswas…·Gary C. Chan

This study shows virion-associated US28 modulates Akt activity to suppress HCMV lytic replication in monocytes, enabling quiescent infection.

DOI 10.1101/2023.09.05.556359

humanexperimental assay

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