Iliana Georgana

This study assesses cross-neutralisation of sarbecoviruses by COVID-19 vaccines in older adults, finding reduced neutralisation of Omicron variants and some animal sarbecoviruses but enhanced neutralisation of specific bat and pangolin coronaviruses.

This paper identifies 2B* as an EMCV protein that antagonizes innate immune signaling by interacting with 14-3-3 proteins, specifically through the RRNSS sequence.

This study shows that the porcine sapovirus protease NS6 inhibits type I IFN production by targeting TBK1, revealing a mechanism for immune evasion and establishing a new cell line model for PSaV research.

This study shows that the cGAS-STING pathway restricts noroviruses by detecting leaked genomic and mitochondrial DNA, leading to IFN responses.

This study analyzes within-host genetic diversity in 1,181 SARS-CoV-2 samples, finding high mutation rates, strand asymmetries, and purifying selection, with implications for transmission chain reconstruction.

This study identifies SPSB1 as a negative regulator of NF-κB activation, showing its specificity for NF-κB and its role in inflammation and innate immunity.