Author

Boyan Yin

Innovative Genomics InstituteORCID 0000-0002-9023-6265Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Hesong HaniD· 2 shared Niren MurthyiD· 2 shared Aijun WangiD· 1 shared Atip LawanprasertiD· 1 shared Benjamin W. BurgstoneiD· 1 shared Bryant XuiD· 1 shared Diana Lee FarmeriD· 1 shared Hengyue SongiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

Hesong HanORCID

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2 papers

Recent·Most cited

BioengineeringNature BiotechnologyPeer-reviewedOct 16, 2024

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP

Kai Chen, Hesong Han, Sheng Zhao…·Jennifer A. Doudna

This study demonstrates that lipid nanoparticle-delivered thermostable Cas9 RNPs achieve high-efficiency genome editing in mouse liver and lung tissues.

214 citationstop 1%

mouseCRISPR screen

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 14, 2022

Non-viral gene editing in utero with lipid nanoparticles complexed to mRNA

Kewa Gao, Jie Li, Hengyue Song…·Aijun Wang

This study demonstrates that lipid nanoparticles can deliver mRNA for gene editing enzymes in utero, effectively editing multiple organs with low toxicity.

DOI 10.1101/2022.10.14.512310

mouseexperimental assay

𝕏 PostBluesky