William C. Faquin

This study develops antibody-peptide epitope conjugates (APECs) to enhance anti-tumor activity in ICB-resistant HNSCC by leveraging viral peptide-loaded MHC I proteins and protease activity.

This study uses scRNA-seq to analyze HPV-related multiphenotypic sinonasal carcinoma and finds an association between HPV and MYB expression, with potential prognostic implications.

This study identifies low HLA/B2M class I expression in ACC tumors and shows it can be reversed by interferon-ψ or STING agonists, suggesting a path for immunotherapy.

This study shows that PI3K pathway alterations in HPV-negative HNSCC are linked to poor outcomes and immune suppression, and that inhibiting PI3K can enhance immune response.