Judith Mantell

This study investigates the functional roles of TANGO1S domains in maintaining ER-Golgi architecture by analyzing domain-deletion mutants in knockout cells.

This paper develops a cryo-FIB lift-out and electron tomography workflow to image bacteria-nanostructure interfaces under native hydrated conditions.

The paper shows how houseflies maintain visual accuracy during fast motion by using synaptic high-frequency jumping, which enhances visual bandwidth and reduces delays.

This study shows that cargo-sensitive TPR switch in kinesin-1 controls its conformational dynamics by dislocating the TPR shoulder, promoting motor domain activation and microtubule binding.

The paper uses cryoET to show cofilin-bound F-actin within platelet microtubules, revealing physiological actin-microtubule hybrids formed under mechanical stress.

The paper engineers an allosteric switch in kinesin-1 motors using de novo peptides, showing increased transport in cells through conformational changes.

This study describes a de novo designed polypeptide that forms phase-separated droplets and fibers, showing droplet maturation into β-conformations similar to pathological assemblies.

This paper isolates a new Streptomyces species from a deep-sea sponge and identifies six unique biosynthetic gene clusters through comparative analysis.

This paper designs peptides that self-assemble into nanoparticles or sheets based on disulfide bond placement, using computational modeling and microscopy.