Yoh‐suke Mukouyama

The paper shows obesity causes capillary leakage in skin, leading to NGF production and pain hypersensitivity, suggesting capillary permeability as a therapeutic target.

This study shows that endothelial Prox1 overexpression disrupts the blood-brain barrier by downregulating BBB-associated genes and Wnt/β-catenin signaling during both embryonic and postnatal stages.

This study identifies NGF-TrkA-PI3K signaling in keratinocyte-nociceptor interactions as a driver of obesity-induced small fiber neuropathy and suggests targeting these interactions as a therapeutic strategy.

The paper shows blood flow promotes neuronal migration in the adult brain by enhancing ghrelin signaling, which aids in olfactory function during food-seeking behavior.

This study identifies distinct roles for Notch4 and canonical Notch signaling in embryonic dermal lymphangiogenesis using mouse models.