Emily V. Dutrow

The paper shows that turnover of CpG islands in enhancers is linked to changes in enhancer activity across mammals, including humans, and contributes to gene regulatory innovation.

The paper identifies ten major canine genetic lineages and their behavioral correlates, showing breed diversification is driven by non-coding regulatory variation.

The paper examines the role of the human-specific enhancer HACNS1 in human evolution by analyzing its effects on gene expression in humanized mice.

The paper disrupts the major promoter-enhancer interaction for Pitx1 in mice and finds minimal phenotypic effects despite complete disruption of the topological interaction.