Author

Dermot Harnett

Max Delbrück CenterORCID 0000-0002-9190-128XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Uwe OhleriD· 3 shared Agnieszka Münster‐WandowskiiD· 2 shared Christian M. T. SpahniD· 2 shared Ekaterina V. BorisovaiD· 2 shared Koshi ImamiiD· 2 shared Markus LandthaleriD· 2 shared Mateusz C. AmbrozkiewicziD· 2 shared Matthew L. KraushariD· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Uwe OhlerORCID

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4 papers

Recent·Most cited

NeuroscienceNature Structural & Molecular BiologyPeer-reviewedDec 1, 2022

A critical period of translational control during brain development at codon resolution

Dermot Harnett, Mateusz C. Ambrozkiewicz, Ulrike Zinnall…·Matthew L. Kraushar

The paper measures translation dynamics in mouse neocortex neurogenesis, revealing a critical period of translational control that regulates protein expression and neuronal differentiation.

68 citationstop 4%

mouseproteomics

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GeneticsbioRxivPreprintOct 8, 2021

Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs

Alessa R. Ringel, Quentin Szabo, Andrea M. Chiariello…·Michael I. Robson

The paper shows that divergent gene expression within TADs is resolved through TAD restructuring and DNA methylation, not enhancer-promoter compatibility or position.

4 citations

mousehuman

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NeuroscienceMolecular CellPeer-reviewedDec 22, 2020

The architecture of protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit

Matthew L. Kraushar, Ferdinand Krupp, Dermot Harnett…·Christian M. T. Spahn

The paper reveals Ebp1's role in neuronal proteostasis by analyzing ribosomal architecture and proteomic changes in the developing mouse neocortex.

49 citations

mouseproteomics

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BioinformaticsbioRxivPreprintApr 8, 2019

Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data

Lorenzo Calviello, Dominique Sydow, Dermot Harnett, Uwe Ohler

Ribo-seQC is a software package that evaluates ribosome profiling data quality and translational profiles across cytoplasmic and organellar ribosomes, outputting shareable platform-independent HTML reports.

48 citations

Ribo-seqstatistical model

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