Combining the alpha-2 adrenergic agonist clonidine with naloxone rescues fentanyl-induced physiologic dysfunction and increases survival
Alyssa Rivera, William E. Schutzer, Alex Sonneborn…·Randy Torralva
This study shows that combining naloxone with clonidine rescues fentanyl-induced respiratory and cardiovascular failure in rats, improving survival by reopening the airway.