Renfeng Li

This paper identifies HNRNPA2B1 as an epigenetic repressor of Epstein-Barr virus reactivation by facilitating histone demethylase recruitment to viral promoters.

This study identifies PIAS1-mediated SUMOylation of EBNA1 as critical for suppressing EBV lytic replication and enhancing episome maintenance.

This study shows that inhibiting SUMOylation with TAK-981 stabilizes cBAF complexes and disrupts the SS18::SSX-driven transcriptome in synovial sarcoma, leading to tumor inhibition.

This paper shows HPV16 replication converts SAMHD1 into a homologous recombination factor by phosphorylation, enhancing its recruitment to viral DNA and reducing replication.

This paper shows that CK2 phosphorylation of HPV16 E2 on serine 23 promotes interaction with TopBP1, which is critical for plasmid retention and HPV16 immortalization of keratinocytes.