Author
Virginia Commonwealth UniversityORCID 0000-0001-5696-2426Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Ronald D. Hill, Krista M. Dalton, Richard Kurupi…·Anthony C. Faber
This study shows that Daraxonrasib (RMC-6236) effectively targets RAS-mutant neuroblastoma by inhibiting MAPK signaling and enhancing cell death.
Febri Gunawan Sugiokto, Kun Zhang, Yunash Maharjan, Renfeng Li
This study identifies PIAS1-mediated SUMOylation of EBNA1 as critical for suppressing EBV lytic replication and enhancing episome maintenance.
Konstantinos V. Floros, Carter K. Fairchild, Jinxiu Li…·Anthony C. Faber
This study shows that inhibiting SUMOylation with TAK-981 stabilizes cBAF complexes and disrupts the SS18::SSX-driven transcriptome in synovial sarcoma, leading to tumor inhibition.
Claire D. James, Aya H. Youssef, Apurva Tadimari Prabhakar…·Iain M. Morgan
This paper shows HPV16 replication converts SAMHD1 into a homologous recombination factor by phosphorylation, enhancing its recruitment to viral DNA and reducing replication.