GeneticsbioRxivPreprint
Short-read whole-genome sequencing identifies the Tg(Tal1-cre/ERT)42-056Jrg transgene insertion site on mouse chromosome 4
Xiaodi Wu, Maya C. Bagish, Pablo Sánchez Vela…·Ross L. Levine
DOI 10.64898/2026.11.04.764251
Author
Pablo Sánchez Vela
Memorial Sloan Kettering Cancer CenterORCID 0000-0002-9286-8290Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 31 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Cancer BiologybioRxivPreprint
TET2 and TP53 Mutations Cooperatively Modulate the Response to Inflammation to Promote Leukemic Transformation
Pablo Sánchez Vela, Brianna Kelly, Claudia Brady…·Alan H. Shih
This study shows that TET2 and TP53 mutations work together to promote leukemic transformation by altering inflammatory responses and chemotherapy tolerance in hematopoietic stem cells.
DOI 10.64898/2026.01.20.700390 - Cancer BiologybioRxivPreprint
Targetable Treatment Resistance in Thyroid Cancer with Clonal Hematopoiesis
Vera Tiedje, Pablo Sánchez Vela, Julie L. Yang…·Ross L. Levine
This study identifies TET2-mutant clonal hematopoiesis in thyroid cancer microenvironments and shows that TGFβ signaling from these macrophages mediates resistance to BRAF/MEK inhibition, with TGFβ inhibition restoring sensitivity.