Tomoyuki Murano

RFind-sc maps single cells onto biological axes defined by external gene signatures, revealing cell states and candidate genes for stress responses.

The paper shows that repetitive neuronal activation induces nuclear reprogramming, leading to cellular maturation state changes with behavioral effects similar to ECT.

This study decodes multiple navigational information types from DG neuron activity in mice, showing independent encoding of position, speed, motion direction, and future location.

The paper identifies a shared transcriptomic pseudoimmaturity induced by neural hyperexcitation across multiple neuropsychiatric disorders.