Author

Anchel De Jaime-Soguero

Leuven Stem Cell InstituteORCID 0000-0002-9358-3676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Frederic Lluı́siD· 2 shared Paraskevi AthanasouliiD· 2 shared Youssef El LaithyiD· 2 shared Adrian JaniszewskiiD· 1 shared Alejandra BrunaiD· 1 shared Alessandra QualizzaiD· 1 shared An ZwijseniD· 1 shared Anirudh PabbaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Frederic Lluı́sORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 27, 2025

Long-term prevention of aneuploidy in human pluripotent stem cells by fine-tuning GSK3 activity

Anchel De Jaime-Soguero, Mírian Romitti, Sabine Costagliola…·S.P. Acebrón

This study shows that low-dose GSK3 inhibitors prevent aneuploidy in hPSCs by reducing mitotic DNA synthesis and ultra-fine chromosome bridges during long-term culture.

1 citation

humanbulk RNA-seq

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Cancer BiologyCancer ResearchPeer-reviewedOct 21, 2025

Chemotherapy-treated breast cancer cells activate the Wnt signaling pathway to enter a diapause-DTP state.

Youssef El Laithy, Willy Antoni Abreu de Oliveira, Anirudh Pabba…·Frederic Lluís

This study shows chemotherapy induces a Wnt-active diapause-DTP state in breast cancer cells, which can be targeted by combined Wnt and chemotherapy inhibition.

6 citations

humanbulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedMar 3, 2023

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

Paraskevi Athanasouli, Martina Balli, Anchel De Jaime-Soguero…·Frederic Lluı́s

This study shows that Wnt/TCF7L1 repression promotes primitive endoderm differentiation in mESCs by inhibiting naive and formative pluripotency factors.

31 citations

mousebulk RNA-seq

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