Claudia Fischbach

This paper develops a shape factor analysis method to quantify spheroid and organoid morphology, showing it provides more reliable morphology assessments than standard shape descriptors.

The paper investigates bone matrix mineralization in the CAM assay, finding that vascular integration and matrix remodeling govern mineral deposition.

This study uses adipose-mimetic hydrogels to show that soft mechanical cues from adipocytes enhance breast cancer cell invasion by altering ECM structure and cellular confinement.

This study shows that large adipocytes release lipids via extracellular vesicles, promoting breast cancer cell migration and proliferation, and links this to human dyslipidemia and triglyceride levels.

This paper introduces FPRM, a fast, label-free imaging method to monitor cellular metabolism using NAD(P)H autofluorescence, and demonstrates its application in tracking metabolic changes under various perturbations.

This study shows that bone mineral density influences tumor growth by altering microenvironmental complexity in an organism-dependent manner.

This study shows that collagen mineralization increases NK cell resistance in breast cancer by thickening the tumor cell glycocalyx through enhanced sialylation.