Author

Lin Lyu

Shanghai Jiao Tong UniversityORCID 0000-0002-9401-7449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Lei CheniD· 3 shared Bing SuiD· 2 shared Michael P. SnyderiD· 2 shared Ru FengiD· 2 shared Xin ZhouiD· 2 shared Alessandra CelliiD· 1 shared Alexander T. HonkalaiD· 1 shared Andrew W. BrooksiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

Lei ChenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologyCell Host & MicrobePeer-reviewedMar 12, 2024

Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

Xin Zhou, Xiaotao Shen, Jethro S. Johnson…·Michael P. Snyder

This study tracks microbiome changes across four body sites in 86 participants over six years, revealing site-specific stability, individualized dynamics, and altered patterns in insulin-resistant individuals.

182 citationstop 1%

humanmetagenomics

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GenomicsGenome ResearchPeer-reviewedMar 1, 2023

Simultaneous Profiling of Host Expression and Microbial Abundance by Spatial Meta-Transcriptome Sequencing

Lin Lyu, Xue Li, Ru Feng…·Lei Chen

The paper develops a pipeline to profile both host expression and microbial abundance from spatial transcriptomic data, demonstrating host-microbe interactions and method efficiency.

21 citations

humanmouse

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BioinformaticsbioRxivPreprintApr 16, 2020

Meta-transcriptomic analysis reveals the gene expression and novel conserved sub-genomic RNAs in SARS-CoV-2 and MERS-CoV.

Lin Lyu, Ru Feng, Mingnan Zhang…·Lei Chen

The paper analyzes meta-transcriptomic data to identify gene expression and novel conserved sub-genomic RNAs in SARS-CoV-2 and MERS-CoV, revealing new peptides with potential functional roles in viral virulence.

5 citations

metagenomicsstatistical model

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