Sophie Bleves

This study identifies TpeX as a pore-forming T6SS effector in P. aeruginosa that disrupts bacterial membranes, with its activity regulated by an immunity protein.

This study characterizes Tle1, a bactericidal toxin from Pseudomonas aeruginosa, and identifies its interactions with VgrG4a, Tla1, and Tli1a, revealing the molecular mechanisms of its delivery and inhibition.

This study shows bacterial Hsp90 stabilizes megasynthases required for virulence factor production in E. coli and P. aeruginosa.

This paper identifies Tle3 and Tli3 as a novel antibacterial toxin-immunity pair in Pseudomonas aeruginosa and shows VgrG2b functions as a trans-kingdom effector targeting both bacteria and eukaryotes.