Qing‐Jun Meng

This study shows that heat pulses can restore circadian rhythms in cartilage by modulating heat shock proteins and circadian clock genes.

This study shows macrophages enhance collagen deposition in fibroblasts through circadian regulation, with M2 macrophages using PDGFA to strengthen circadian rhythms and increase collagen production.

Heat shock, dexamethasone and osmotic stress all entrain the clock of primary mouse chondrocytes but yield distinct rhythmic transcriptomes, overlapping only marginally with each other and in vivo cartilage.

This study compares circadian rhythms in photoprotected and photoexposed human skin, finding reduced rhythmic genes and advanced peak times in sun-exposed skin.

The paper uses stable isotope labeling and mass spectrometry to show that tendon ECM has circadian and permanent pools with distinct turnover rates, which change with age.

The paper quantifies circadian interactions and protein abundance to reveal mechanisms maintaining the circadian clock's operational stability.