Martina Bazzaro

This study shows that ARID1A loss in ovarian clear cell carcinoma maintains increased mitochondrial respiration and bioenergetic efficiency under metabolic challenges, with specific ETC protein changes.

This study identifies UNC-45A as an ATP-independent microtubule severing protein that inhibits repair of defects, leading to microtubule loss and neurite dystrophy in Alzheimer's disease.

This paper shows UNC-45A increases microtubule curvature and counteracts Taxol's straightening effects, suggesting a role in drug resistance.

The paper identifies UNC-45A expression in proliferative cells of the mouse genital tract and microtubule-rich areas of the nervous system, suggesting its potential role in ovarian cancer and neurodegeneration.