Mridula Annaswamy Srinivas

This study identifies a single amino acid mutation in norovirus NS4 that rescues replication defects of a specialist virus, enabling it to spread more efficiently in vitro.

This study identifies Trim47 as a host restriction factor that inhibits murine norovirus strain CR6 but not strain CW3, revealing strain-specific antiviral mechanisms.

This study shows Trim7 does not restrict murine norovirus infection in vivo, despite its antiviral activity in cell culture.