Plscr1 inhibits murine norovirus entry
Nina S. Baggett, Linley R. Pierce, Robert C. Orchard
This study identifies Plscr1 as a restriction factor for murine norovirus, showing it inhibits infection through a post-attachment entry step.
Author
The University of Texas Southwestern Medical Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Nina S. Baggett, Linley R. Pierce, Robert C. Orchard
This study identifies Plscr1 as a restriction factor for murine norovirus, showing it inhibits infection through a post-attachment entry step.
Stacey L. Crockett, Linley R. Pierce, Rachel Rodgers…·Robert C. Orchard
This study identifies Trim47 as a host restriction factor that inhibits murine norovirus strain CR6 but not strain CW3, revealing strain-specific antiviral mechanisms.
Mridula Annaswamy Srinivas, Linley R. Pierce, Mikayla C. Olson…·Robert C. Orchard
This study shows Trim7 does not restrict murine norovirus infection in vivo, despite its antiviral activity in cell culture.
Mikayla C. Olson, Linley R. Pierce, Robert C. Orchard
This paper develops a luciferase-based reporter system for murine norovirus to study replication and screen antiviral compounds.
Brittany M. Stewart, Linley R. Pierce, Mikayla C. Olson…·Robert C. Orchard
This study shows that lipid asymmetry, mediated by TMEM30a, is essential for murine norovirus entry and persistent infection.