Josh Titlow

This paper introduces Deep3DSIM, an upright 3D-SIM system with adaptive optics for deep tissue imaging, achieving high-quality imaging up to 130 micrometers in Drosophila brain.

The paper localizes specific mRNAs in Drosophila Mushroom Body Output Neurons before and after aversive olfactory learning, showing cell-specific abundance and a transient increase in CaMKII mRNA.

This study identifies Syncrip/hnRNPQ as a regulator of activity-induced Msp300/Nesprin-1 expression and new synapse formation through local translation.

This paper applies single-molecule FISH to study post-transcriptional regulation in Drosophila brains by analyzing mRNA distributions and co-visualizing transcripts and proteins.