José Antonio Bengoechea

This paper shows that SdiA in Klebsiella pneumoniae represses phagocytosis and intracellular survival, with mutant strains being more susceptible to phagocytosis but showing increased intracellular fitness and host cell death.

This study identifies simple sequence repeats in rmpA and rmpD/rmpC genes that mediate phase variation of the mucoid phenotype in hypervirulent Klebsiella pneumoniae, enabling adaptation to different infection niches.

This study shows Klebsiella pneumoniae modifies its lipid A in response to macrophage environment, enhancing survival and immune evasion through TLR4-dependent mechanisms.

The paper investigates how lipid A modifications in Yersinia species influence pathogenicity by altering TLR4 recognition and inflammation.

This study shows Klebsiella pneumoniae inhibits vasodilation by targeting eNOS post-translational modifications through its T6SS and capsule polysaccharide.

This study uses Bac-CyTOF to analyze immune cell interactions with Klebsiella pneumoniae in mice, revealing changes in immune cell populations and the role of T6SS and STING in infection outcomes.

The paper introduces an ion mobility-integrated gas phase fractionation (IM-GPF) method for rapid diaPASEF library generation, outperforming direct deconvolution and approaching offline fractionation performance.