Hans‐Michael Tautenhahn

This study compares lobular geometry and CYP450 zonation across four species using whole slide imaging, identifying species differences and determining the minimum number of lobules needed for statistical analysis.

This paper develops a PBPK model of talinolol to study P-gp function and its impact on pharmacokinetics under various conditions.

This study develops a PBPK model to assess CYP2E1 activity using chlorzoxazone, showing how ethanol consumption, abstinence, and liver impairment affect its metabolism.