PathologyFrontiers in PharmacologyPeer-reviewed
Cross-Species Variability in Lobular Geometry and Cytochrome P450 Hepatic Zonation: Insights into CYP1A2, CYP2E1, CYP2D6 and CYP3A4
Mohamed Albadry, Jonas Küttner, Jan Grzegorzewski…·Uta Dahmen
This study compares lobular geometry and CYP450 zonation across four species using whole slide imaging, identifying species differences and determining the minimum number of lobules needed for statistical analysis.