BioinformaticsiSciencePeer-reviewed
Exploration of cell development pathways through high dimensional single cell analysis in trajectory space
Denis Đermadi, Michael Bscheider, Kristina Bjegovic…·Eugene C. Butcher
The paper introduces tSpace, a computational method for analyzing developmental pathways in single-cell data, and shows it reconstructs known developmental sequences and reveals new insights into B cell development and intestinal epithelial differentiation.