Michael Ratz

The paper uses in utero barcoding and single-cell transcriptomics to map clonal relationships in mouse mesoderm-derived tissues, revealing lineage relationships in liver and heart mesenchyme.

The paper develops a method for in situ genotyping of bacterial libraries using chromosomally expressed barcodes to measure intracellular maturation times of red fluorescent proteins.

This study determines the molecular organisation of the human prohibitin complex within the mitochondrial inner membrane using structural biology methods.

The paper profiles clonal landscapes in mouse embryos to reveal spatial modulators of clonal fate biases using single-cell lineage tracing and clone2vec.

The paper identifies heritable transcriptional diversity within cell types by studying clonal human lymphocytes and mouse brain cells, showing clone-specific chromatin accessibility leads to distinct gene expression.

This study uses single-cell and spatial transcriptomics to reveal clonal relationships and cell types in the mouse brain, showing fate-restricted progenitor cells and microglia origins.

The paper introduces STRT-seq-2i, a high-throughput single-cell RNA-seq platform, and demonstrates its application on fresh mouse and frozen human cortical samples.