Author

Margaret Frances J. Lee

Duke UniversityORCID 0000-0002-9804-3193Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Arinze Emmanuel OkaforiD· 1 shared Cameron MartinoiD· 1 shared Daniel T. McDonaldiD· 1 shared Dimitry N. KrementsoviD· 1 shared Eamonn R. Heney· 1 shared Emily A Nelson· 1 shared Gibraan RahmaniD· 1 shared Huiying SuniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPathology

Arinze Emmanuel OkaforORCID

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2 papers

Recent·Most cited

BioinformaticsmSystemsPeer-reviewedAug 11, 2026

Integrated multi-omics analysis identifies microbial and metabolic signatures and drivers of CNS autoimmunity

Theresa L. Montgomery, Emily A Nelson, Lauren A Downs…·Dimitry N. Krementsov

This paper integrates microbiomic and metabolomic data to identify microbial and metabolic drivers of CNS autoimmunity in a mouse model of MS.

DOI 10.1128/msystems.00002-26

mousemetagenomics

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PathologyJournal of Investigative DermatologyPeer-reviewedMay 23, 2024

UBE2N is essential for maintenance of skin homeostasis and suppression of inflammation

Margaret Frances J. Lee, Manel Ben Hammouda, Wanying Miao…·Jennifer Y. Zhang

This study shows that UBE2N is crucial for skin homeostasis and inflammation suppression, with its loss causing inflammatory skin defects and identifying IRAK1/4 as a therapeutic target.

11 citations

mousebulk RNA-seq

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