Yong Yu

The paper identifies a neuropeptide signaling cascade in C. elegans that promotes lipid catabolism under dietary restriction and during starvation.

This study identifies LCA's mechanism of action through TULP3-sirtuin-v-ATPase-AMPK pathway to activate AMPK and extend lifespan in model organisms.

This study shows FITM2 deficiency reduces VLDL triglyceride secretion and causes ER stress and lipid accumulation in liver cells and mice.

This study identifies SLC29A homologs in C. elegans that mediate nucleoside coordination between soma and germline, revealing guanosine as critical for reproduction.