Cancer BiologybioRxivPreprint
Cell of origin alters myeloid-mediated immunosuppression in lung adenocarcinoma
Minxiao Yang, Noah Shulkin, Edgar Gonzalez…·Crystal N. Marconett
This study shows that the cell of origin in lung adenocarcinoma affects the immunosuppressive state of the tumor microenvironment, with AT1-derived tumors showing an anti-tumor immune profile and AT2-derived tumors showing immunosuppressive features.
DOI 10.1101/2024.06.19.599651