Crystal N. Marconett

The paper identifies regeneration-associated transitional progenitors (RATPs) in Cldn18 knockout mice, showing they are less fibrogenic and contribute to lung repair rather than fibrosis.

This study shows that different culture media significantly alter the inflammatory phenotype and functional properties of human tracheo-bronchial basal stem cells.

This study shows that the cell of origin in lung adenocarcinoma affects the immunosuppressive state of the tumor microenvironment, with AT1-derived tumors showing an anti-tumor immune profile and AT2-derived tumors showing immunosuppressive features.

The paper identifies TRIP13 as a mediator of AT2 cell dysfunction in IPF through integrated transcriptomic and epigenomic analysis and shows TRIP13 inhibition prevents mesenchymal gene signature acquisition.

The paper identifies GRAMD2+ alveolar type I cells as plastic and capable of transitioning through multiple lung epithelial cell states in organoid culture.

This study identifies key epigenetic states and transcription factor networks in human alveolar epithelial differentiation, revealing dynamic enhancer changes and regulatory interactions critical for distal lung identity.