Author

Seungyoon B. Yu

University of California San DiegoORCID 0000-0002-9910-6029Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Seungyoon B. Yu1 paper · Denali Therapeutics (United States)

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Gülçin PekkurnaziD· 4 shared Haoming WangiD· 3 shared Ahmed A. AbushawishiD· 2 shared Andrew J. ZhangiD· 2 shared Majid GhassemianiD· 2 shared Natasha M. CarlsoniD· 2 shared Richard G. SáncheziD· 2 shared Abhishek SingharoyiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

Gülçin PekkurnazORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NeuroscienceDevelopmental CellPeer-reviewedJun 5, 2024

Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity

Seungyoon B. Yu, Haoming Wang, Richard G. Sánchez…·Gülçin Pekkurnaz

This study shows that neuronal activity increases mitochondrial O-GlcNAcylation, which helps neurons meet energy demands based on fuel availability.

32 citationstop 5%

statistical model

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Cell BiologybioRxivPreprintOct 13, 2023

FluxNorm: Toolbox for metabolic flux assay normalization by in situ cell counting

Nathalie A. Djaja, Teva Bracha, Seungyoon B. Yu…·Gulcin Pekkurnaz

FluxNorm normalizes metabolic flux data by in situ cell counting to accurately assess cellular bioenergetics across experimental conditions.

DOI 10.1101/2023.10.13.562314

metabolomicsstatistical model

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NeurosciencebioRxivPreprintAug 26, 2023

Functional Organization of Glycolytic Metabolon on Mitochondria

Haoming Wang, John Vant, Youjun Wu…·Gülçin Pekkurnaz

This study identifies OGT-mediated O-GlcNAcylation of HK1 as a mechanism regulating glycolytic metabolon assembly on mitochondria, enhancing ATP production and synaptic function.

5 citations

humanproteomics

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BioinformaticsNature MethodsPeer-reviewedMar 8, 2021

Deep Learning-Based Point-Scanning Super-Resolution Imaging

Linjing Fang, Fred Monroe, Sammy Weiser Novak…·Uri Manor

This paper introduces a deep learning method to enhance the resolution and speed of point-scanning imaging systems by restoring undersampled images.

203 citationstop 1%

imagingdeep learning

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