Manuel A. Torres Acosta

This paper introduces RREM-seq, an enzyme-based reduced representation DNA methylation sequencing method that enables high-resolution profiling of low-input samples, including clinical specimens.

This study shows that FOXP3+ Treg cells use TBET to control activated CD8+ T cells during influenza recovery, but not Trm cell generation.

This study shows AMPK is necessary for Treg cell adaptation to metabolic stress in tumors and lung injury but not for baseline immune homeostasis.

This study shows that DNA methylation via UHRF1 is essential for iTregs to promote lung recovery after viral pneumonia.