Florian Ingo Schmidt

This study shows human NLRC4 can directly sense cytosolic flagellin without NAIP, while NAIP may inhibit this response.

This study shows that MECP2 inhibits cGAS signaling by exporting to the cytosol upon dsDNA detection, dampening inflammation and antiviral responses.

This paper uses lipid nanoparticles to deliver mRNA encoding intrabodies that inhibit necroptosis and pyroptosis by targeting MLKL and ASC, respectively.

This paper develops a fluorescent reporter to visualize and quantify endogenous inflammasome assembly and caspase-1 recruitment in real-time.