Opposing roles of ACE2 and TMPRSS2 in IBV Beaudette infection
Yuan Cao, Yannis Long, Sabrina Schleibinger…·Hicham Sid
This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.
Author
Technical University of MunichORCID 0000-0002-9990-1890Unclaimed ORCID profile · follow to get notified of new preprints
10 papers
Recent·Most cited
Yuan Cao, Yannis Long, Sabrina Schleibinger…·Hicham Sid
This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.
Theresa M. Pauli, Theresa von Heyl, Beate Rieblinger…·Benjamin Schusser
This study evaluates virus-like particles (VLPs) as efficient delivery vehicles for genome editing tools in pigs and chickens, achieving high editing rates in various cell types and systems.
Theresa von Heyl, Milena Brunner, Antonia Schmauser…·Benjamin Schusser
This study uses scRNA-seq to analyze γδT cells in TCR KO chickens, identifying novel gene markers and functional characteristics of β and γδ T cell subsets.
Hicham Sid, Theresa von Heyl, Sabrina Schleibinger…·Benjamin Schusser
This study reinstates RIG-I and RNF135 in chickens to investigate their role in avian influenza response, finding that their expression exacerbates inflammation and mortality without affecting viral replication.
Milena Brunner, Catarina L. C. T. Cavaleiro, T.V.L. Berghof…·Benjamin Schusser
The paper investigates molecular mechanisms of B cell migration to the bursa of Fabricius in chicken embryos, identifying roles for CCR7, CXCR4, and cell adhesion molecules.
Felix Tetzlaff, Ulrich Methner, Theresa von Heyl…·Angela Berndt
This study shows that γδ T cells help protect chickens early against Salmonella infection, but their role is replaced by other cells later.
Mohanned Naif Alhussien, Hanna-Kaisa Vikkula, Romina Klinger…·Benjamin Schusser
This study creates IFN receptor knockout chickens to investigate IFN dynamics in influenza infection, revealing strain-specific roles and highlighting type I IFN's importance in initial defense against H3N1.
Mohammad A. Sabsabi, Ahmed Kheimar, Yu You…·Benedikt B. Kaufer
This study shows that γδ T cells restrict Marek's disease virus replication and tumor formation in chickens by reducing viral load in key lymphoid organs.
Sandra Kollmansperger, Malte Anders, Julia Werner…·Thomas Fenzl
The paper investigates the development of electroencephalic neuronal activity in chicken embryos to determine when nociception might begin, finding that noxious stimuli may be processed by day 13.
Denise Bartsch, Hicham Sid, Beate Rieblinger…·Benjamin Schusser
This paper generates Cas9-expressing transgenic chickens and pigs for in vivo genome editing, demonstrating their health, fertility, and functionality across multiple tissues and genes.