Opposing roles of ACE2 and TMPRSS2 in IBV Beaudette infection
Yuan Cao, Yannis Long, Sabrina Schleibinger…·Hicham Sid
This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.
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Technical University of MunichORCID 0000-0002-5608-8166Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Yuan Cao, Yannis Long, Sabrina Schleibinger…·Hicham Sid
This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.
Mohanned Naif Alhussien, Hanna-Kaisa Vikkula, Romina Klinger…·Benjamin Schusser
This study creates IFN receptor knockout chickens to investigate IFN dynamics in influenza infection, revealing strain-specific roles and highlighting type I IFN's importance in initial defense against H3N1.
Denise Bartsch, Hicham Sid, Beate Rieblinger…·Benjamin Schusser
This paper generates Cas9-expressing transgenic chickens and pigs for in vivo genome editing, demonstrating their health, fertility, and functionality across multiple tissues and genes.