Ji‐Dung Luo

This study shows that short-term gonadal cultures of zebra finch PGCs can produce germline chimeras and validated offspring, despite being heterogeneous, unlike long-term chicken PGC cultures.

The paper identifies mTOR activation in POMC neurons as a key mechanism causing leptin resistance in diet-induced obese mice.

This study compares germ cell development between chicken and zebra finch using single-cell RNA sequencing, revealing distinct early germ cell types in zebra finch that are absent in chicken.

The paper identifies layer 5a corticostriatal neurons as selectively vulnerable in Huntington's disease using single nucleus RNA sequencing and shows they have extensive mHTT-CAG expansions.

This study investigates YAP's role in early ectodermal specification and its link to Huntington's Disease using human neuruloids, finding YAP activation influences ectodermal fate and that reducing YAP activity can partially rescue HD phenotypes.