Timothy L. Domeier

This study identifies a Gαq/11-IP3R1-ANO1 signaling axis responsible for pressure-induced lymphatic contractions in mouse popliteal vessels.

This study identifies TRPV4-expressing macrophages as regulators of lymphatic vessel function through TXA2 receptors, suggesting therapeutic targets for lymphedema.

This study shows that dystrophin-deficient mice exhibit age-dependent RV contractile dysfunction and arrhythmia under preload/afterload challenge, with greater damage in middle-aged hearts.

This study examines atrial tachyarrhythmias in ex vivo aged mouse hearts under hypokalemia and right atrial stretch, finding that combined challenges induce atrial tachycardia or AF/AFL in 50% of hearts.