Author

James L. Hougland

Syracuse UniversityORCID 0000-0003-0444-1017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ali Zareein· 2 shared Jimmy Blauser-Wilson· 2 shared Sao PuthiD· 2 shared Shruti Sunil JadhaviD· 2 shared Yaoying WuiD· 2 shared Abigail Marie Hernandez· 1 shared Andrea A Joseph· 1 shared Andrea M. Sprague-GetsyiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

Ali Zareein

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 29, 2026

Single-Particle STORM Imaging Quantifies Coating Heterogeneity Among Cell Membrane-Coated Nanoparticles

Jimmy Blauser-Wilson, Ali Zareein, Sao Puth…·Yaoying Wu

This paper uses single-particle STORM imaging to quantify membrane coating heterogeneity in cell membrane-coated nanoparticles and reveals cell-type-dependent coating outcomes.

DOI 10.64898/2026.09.28.755175

imagingexperimental assay

𝕏 PostBluesky

BioengineeringACS Biomaterials Science & EngineeringPeer-reviewedOct 4, 2025

Development of Dendritic Cell Membrane-Coated Nanoparticles for Antigen-Specific T Cell Engagement

Sao Puth, Shruti Sunil Jadhav, Ali Zareein…·Yaoying Wu

This study develops a combined coating method for dendritic cell membrane-coated nanoparticles, showing improved protein coating and size control, and validates their antigen-specific T cell engagement.

5 citations

mouseexperimental assay

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BiochemistrybioRxivPreprintFeb 28, 2019

Molecular architecture of a membrane-spanning hormone acyltransferase required for metabolic regulation

Maria B. Campaña, Flaviyan Jerome Irudayanathan, Tasha R. Davis…·James L. Hougland

The paper presents a structural model of GOAT, an MBOAT enzyme, using co-evolutionary constraints and computational modeling validated by biochemistry, revealing a novel acylation mechanism within a transmembrane channel.

DOI 10.1101/556233

humanproteomics

𝕏 PostBluesky