Author

Kaitlin N. Hart

Regeneron (United States)ORCID 0000-0003-0484-1969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

Alena S Bruening· 1 shared Aris N. EconomidesiD· 1 shared David PépiniD· 1 shared Edmund LeachiD· 1 shared Erich J. GoebeliD· 1 shared James Anthony HowardiD· 1 shared John B. Lees‐ShepardiD· 1 shared Krunal PateliD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Alena S Bruening

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 1, 2024

Structural Basis of Non-Latent Signaling by the Anti-Mullerian Hormone Procomplex

James Anthony Howard, Lucija Hok, Richard L. Cate…·Thomas B. Thompson

This study reveals the structural basis of AMH procomplex signaling, showing how the prodomain maintains activity through a unique conformational mechanism.

1 citation

experimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintJan 29, 2024

Coordinate regulation of Activin and Bone Morphogenetic Protein signaling by a lysosomal trafficking switch

Warren W. Hom, Senem Aykul, Lampros Panagis…·Aris N. Economides

The paper shows that ActA forms non-signaling complexes with ACVR1 that are trafficked to lysosomes and degraded, unlike Activin B, AC, and AB which remain on the surface.

1 citation

humanexperimental assay

𝕏 PostBluesky